I have an article published in The Economist's Babbage blog about how some patients with a terminal diseases are second-guessing pharmaceutical companies and medicating themselves. Here's the blurb:
It takes eight years on average for a drug to receive approval from America’s Food and Drug Administration (FDA) after clinical trials have been successfully completed. Some patients of amyotrophic lateral sclerosis (ALS), with a life expectancy of two to five years after diagnosis, do not want to wait that long. Since September 2011 some of those diagnosed with the fatal disease have taken to injecting themselves with a substance whose chemical identity they deduced from published literature, and which they claim is currently being clinically tested.... read more.Here is a set of main references:
- Neuraltus Pharmaceuticals press release
- James Heywood et al. Nature Biotechnology, 2011
- Eric Valor's conjecture
- ALS Study Shows Social Media's Value as Research Tool - The Wall Street Journal
- Frustrated ALS Patients Concoct Their Own Drug - The Wall Street Journal
- PatientsLikeMe - Lithium and ALS, sodium chlorite, NP001
- ALS Chlorite